RESEARCH JOURNAL OF FOOD SCIENCE AND NUTRITION
Integrity Research Journals
ISSN: 2536-7080
Model: Open Access/Peer Reviewed
DOI: 10.31248/RJFSN
Start Year: 2016
Email: rjfsn@integrityresjournals.org
The nutrient profile and in vivo anti-inflammatory properties of methanol-extracted turmeric in Wistar rats
https://doi.org/10.31248/RJFSN2023.160 | Article Number: 9DBDF6A31 | Vol.8 (3) - December 2023
Received Date: 21 October 2023 | Accepted Date: 04 December 2023 | Published Date: 30 December 2023
Authors: Abdulwahab O. Salawu , Maimuna B. Umar , Sakariyau A. Waheed* , Soliu A. Azeez , Chizoba V. Obunadike and Gideon P. Azaki
Keywords: phytochemical, proximate, inflammation, Curcuma longa
Curcuma longa has long been recognized for its anti-inflammatory properties in traditional medicine systems, which has received substantial scientific validation. This study aimed to evaluate C. longa methanolic extract's proximate and anti-inflammatory activities. Phytochemical screening of C. longa was done by colorimetric and spectrophotometric approaches (both qualitative and quantitative respectively). Furthermore, a recent approach (standard method) was used to research C. longa's anti-inflammatory effects and proximate components. The qualitative phytochemical screening revealed a substantial amount of turbid alkaloid (++) but no steroid (-). Phenol (151.34±1.01 mg/100g) had the highest concentration (5.83%), while flavonoid (22.30±0.62 mg/100g) had the lowest (5.83%), according to the quantitative screening. The anti-inflammatory activity of the C. longa methanolic extract in the treated groups (150, 300, and 600 mg/kg body weight) and the positive control group demonstrated a valuable value (inhibitory values). Paw thickness was also significantly different (reduced) between the 600 mg/kg (0.7 cm at 6 hours) and positive control groups (0.5 cm at 6 hours) deducing the anti-inflammatory effects of turmeric when compared to the negative control groups. The lowest inhibition was noted in the 150 mg/kg bw group when compared to 1-6 hours of treatment. These findings demonstrated the anti-inflammatory effects of turmeric and its adjuvant capabilities.
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