Model: Open Access/Peer Reviewed
DOI: 10.31248/JPMMS
Start Year: 2018
Email: jpmms@integrityresjournals.org
https://doi.org/10.31248/JPMMS2025.022 | Article Number: 43FCB9862 | Vol.3 (1) - August 2025
Received Date: 01 April 2025 | Accepted Date: 28 June 2025 | Published Date: 30 August 2025
Authors: Abdulmalik Nihinlola Ajoke , Akpor Oluwaseyi Abiodun , Adeoluwa Oluwasegun Adebayo , Olaniyi Kehinde Samuel , Omoniyi Sunday Oluwafemi* , Anyebe Emmanuel Ejembi , Olukunmi Lanre Olaitan and Paul Mary Kakamision
Keywords: Nigeria., systematic review, Educational Intervention Model, self-management, type 2 diabetes mellitus.
Type-2 diabetes mellitus poses a significant public health challenge in Nigeria, where limited awareness, poor self-management, and inadequate healthcare resources contribute to disease complications, including the risk of Alzheimer’s disease. This paper evaluates educational intervention models designed and implemented to promote and prevent memory impairment among individuals living with T2DM at various levels. The review was conducted using the Centre for Review Dissemination. Online journal databases, including Google Scholar, PubMed, and the Web of Science, were searched extensively for relevant studies published between 2019 and 2023. The selection criteria encompassed qualitative, quantitative, and mixed-method studies that met the inclusion and exclusion guidelines based on the SPIDER framework and provisionally selected 30 studies for the review with detailed of various educational intervention models aimed at improving knowledge, adherence to treatment regimens, and prevention strategies for reducing the risk of Alzheimer’s disease among T2DM patients. The review indicated that the majority of T2DM patients lacked awareness of essential educational components, such as disease promotion, prevention, and adherence strategies. Additionally, some healthcare providers were unaware of the significance of educational intervention models in enhancing service utilisation among adults and elderly patients with T2DM. Following further screening, 20 articles met the inclusion criteria and were analysed for information on educational intervention models and the success levels of pre- and post-intervention strategies. The remaining 10 articles explored intervention models focusing on long-term prognostic approaches to T2DM and its progression to Alzheimer’s disease. These studies stressed the importance of structured educational programs in mitigating memory impairment risks among T2DM patients. The review highlights the critical need for improved health education strategies to prevent cognitive decline among T2DM patients, such as patient-centered programs that teach individuals how to manage their diabetes through knowledge, skills, and confidence-building. Healthcare providers must enhance their skills and attitudes toward the promotion, prevention, and maintenance of health education initiatives. Addressing the existing gaps through targeted intervention programs that can reduce the risk of Alzheimer’s disease among adults and elderly patients in healthcare facilities. Researchers should focus on developing and implementing sustainable educational intervention models tailored to the specific needs of T2DM patients in Nigeria and other similar settings.
| Ali, K. J., Ali, S., Pooyan, A. H. & Mehdi, A. (2023). Effect of educational intervention based on PRECEDE model on lifestyle modification, self-management behaviours, and hypertension in diabetic patients. BMC Endocrine Disorders, 23, Article number 6. https://doi.org/10.1186/s12902-023-01264-y |
||||
| Association of Diabetes Care and Education Specialists, & Kolb, L. (2021). An effective model of diabetes care and education: the ADCES7 Self-Care Behaviors™. The Science of Diabetes Self-Management and Care, 47(1), 30-53. Retrieved from https://pubmed.ncbi.nlm.nih.gov/34078208/ https://doi.org/10.1177/0145721720978154 |
||||
| Atolagbe, E. T., Sivanandy, P., & Ingle, P. V. (2023). Effectiveness of educational intervention in improving medication adherence among patients with diabetes in Klang Valley, Malaysia. Frontiers in Clinical Diabetes and Healthcare, 4, 1132489. https://doi.org/10.3389/fcdhc.2023.1132489 |
||||
| Bagweneza, V., Musabirema, P., Mwiseneza, M. J., Collins, A., & Bhengu, B. R. (2019). Diabetes health education: nurses' knowledge of essential components at a Rwandan hospital. Rwanda Journal of Medicine and Health Sciences, 2(2), 172-177. https://doi.org/10.4314/rjmhs.v2i2.13 |
||||
| Balogh, E. G., Perez-Nieves, M., Cao, D., Hadjiyianni, I. I., Ashraf, N., Desai, U., Snoek, F. J., & Sturt, J. A. (2020). Key strategies for overcoming psychological insulin resistance in adults with type 2 diabetes: The UK subgroup in the EMOTION study. Diabetes Therapy, 11(8), 1735-1744. https://doi.org/10.1007/s13300-020-00856-4 |
||||
| Bică, C., Sandu, C., Suceveanu, A. I., Sarbu, E., Stoica, R. A., Gherghiceanu, F., ... & Stoian, A. P. (2020). Non-alcoholic fatty liver disease: A major challenge in type 2 diabetes mellitus. Experimental and Therapeutic Medicine, 20(3), 2387-2391. https://doi.org/10.3892/etm.2020.8882 |
||||
| Centres for Disease Control and Prevention. (2022). Alzheimer's disease. Retrieved from https://www.cdc.gov/alzheimers-dementia/about/alzheimers.html?CDC_AAref_Val=https://www.cdc.gov/aging/aginginfo/alzheimers.htm | ||||
| Chen, S., Qian, D., Burström, K., & Burström, B. (2020). Impact of an educational intervention in primary care on fasting blood glucose levels and diabetes knowledge among patients with type 2 diabetes mellitus in rural China. Patient Education and Counseling, 103(9), 1767-1773. https://doi.org/10.1016/j.pec.2020.03.010 |
||||
| De la Fuente Coria, M., Cruz-Cobo, C., & Santi-Cano, M. J. (2020). Effectiveness of a primary care nurse delivered educational intervention for patients with type 2 diabetes mellitus in promoting metabolic control and compliance with long-term therapeutic targets: Randomised controlled trial. International Journal of Nursing Studies, 101, 103417. https://doi.org/10.1016/j.ijnurstu.2019.103417 |
||||
| Duarte‐Díaz, A., González‐Pacheco, H., Rivero‐Santana, A., Ramallo‐Fariña, Y., Perestelo‐Pérez, L., Peñate, W., ... & INDICA Team. (2022). Factors associated with patient empowerment in Spanish adults with type 2 diabetes: A cross‐sectional analysis. Health Expectations, 25(6), 2762-2774. https://doi.org/10.1111/hex.13501 |
||||
| Gehlawat, M., Lakshminarayanan, S., & Kar, S. S. (2019). Structured diabetes education program for improving self-care behavior in primary care settings of Puducherry: Evidence from a randomized controlled trial. Indian Journal of Community Medicine, 44(2), 107-112. https://doi.org/10.4103/ijcm.IJCM_192_18 |
||||
| Hadziabdic, E., Pettersson, S., Marklund, H., & Hjelm, K. (2020). Development of a group-based diabetes education model for migrants with type 2 diabetes, living in Sweden. Primary health care research & development, 21, e50. https://doi.org/10.1017/S1463423620000493 |
||||
| Haider, R., Sudini, L., Chow, C. K., & Cheung, N. W. (2019). Mobile phone text messaging in improving glycaemic control for patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Diabetes Research and Clinical Practice, 150, 27-37. https://doi.org/10.1016/j.diabres.2019.02.022 |
||||
| Ibitoba, F. A. (2021). Prevalence and risk factors of chronic kidney disease among commercial motorcyclists in Ado-Ekiti, Ekiti State. (An unpublished M.Sc. dissertation), Afe Babalola University, Ado-Ekiti, Nigeria. https://doi.org/10.1016/j.sciaf.2022.e01136 |
||||
| IDF Diabetes Atlas (2021). IDF Diabetes Atlas 2021. IDF Atlas 10th Edition. Retrieved 17th September 2024 from https://diabetesatlas.org/atlas/tenth-edition/ | ||||
| Ismail, L., Materwala, H., & Al Kaabi, J. (2021). Association of risk factors with type 2 diabetes: A systematic review. Computational and Structural Biotechnology Journal, 19, 1759-1785. https://doi.org/10.1016/j.csbj.2021.03.003 |
||||
| Izquierdo, V., Pazos-Couselo, M., Gonzalez-Rodriguez, M., & Rodriguez-Gonzalez, R. (2022). Educational programs in type 2 diabetes designed for community-dwelling older adults: A systematic review. Geriatric Nursing, 46, 157-165. https://doi.org/10.1016/j.gerinurse.2022.05.008 |
||||
| Jeihooni, A. K., Barati, M., Kouhpayeh, A., Kashfi, S. M., Harsini, P. A., & Rahbar, M. (2019). The effect of educational intervention based on BASNEF model on self-medication behavior of type 2 diabetic patients. Indian journal of Endocrinology and Metabolism, 23(6), 616-622. https://doi.org/10.4103/ijem.IJEM_436_19 |
||||
| Khalooei, A., & Benrazavy, L. (2019). Diabetes self-management and its related factors among type 2 diabetes patients in primary health care settings of Kerman, Southeast Iran. Journal of Pharmaceutical Research International, 29(4), 1-9. https://doi.org/10.9734/jpri/2019/v29i430241 |
||||
| Kirvalidze, M., Hodkinson, A., Storman, D., Fairchild, T. J., Bała, M. M., Beridze, G., ... & Brini, S. (2022). The role of glucose in cognition, risk of dementia, and related biomarkers in individuals without type 2 diabetes mellitus or the metabolic syndrome: A systematic review of observational studies. Neuroscience & Biobehavioral Reviews, 135, 104551. https://doi.org/10.1016/j.neubiorev.2022.104551 |
||||
| Kumar, R., Rehman, S., Baloch, G. M., Vankwani, M., Somrongthong, R., & Pongpanich, S. (2022). Effectiveness of health education intervention on diabetes mellitus among the teachers working in public sector schools of Pakistan. BMC Endocrine Disorders, 22 Article number 194. https://doi.org/10.1186/s12902-022-01110-7 |
||||
| Magliano, D. J., Boyko, E. J., & IDF Diabetes Atlas Writing Group (2021). IDF Diabetes Atlas (10th ed.). International Diabetes Federation. | ||||
| McGuinness, L. A. (2019). "robvis: An R package and web application for visualizing risk-of-bias assessments" [Web application]. Retrieved from from: https://mcguinlu.shinyapps.io/robvis/ https://doi.org/10.1002/jrsm.1411 |
||||
| Michailidis, M., Moraitou, D., Tata, D. A., Kalinderi, K., Papamitsou, T., & Papaliagkas, V. (2022). Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes. International Journal of Molecular Sciences, 23(5), 2687. https://doi.org/10.3390/ijms23052687 |
||||
| Mourão, D. M., Sedlmaier, B. M. G., Pires, V. L. R., & Borges, G. F. (2023). Effectiveness of a diabetes educational intervention at primary school. International Journal of Diabetes in Developing Countries, 43(1), 83-90. https://doi.org/10.1007/s13410-021-01033-4 |
||||
| Najafpour, Z., Zeidi, I. M., & Kalhor, R. (2021). The effect of educational intervention on medication adherence behaviour in patients with type 2 diabetes: application of social marketing model. Clinical Diabetology, 10(4), 359-369. https://doi.org/10.5603/DK.a2021.0040 |
||||
| Okafor, C. N., Akosile, C. O., Nkechi, C. E., Okonkwo, U. P., Nwankwo, C. M., Okoronkwo, I. L., Okpala, P. U., & Afonne, A. J. (2023). Effect of educational intervention programme on the health-related quality of life (HRQOL) of individuals with type 2 diabetes mellitus in South-East, Nigeria. BMC Endocrine Disorders, 23, Article number 75. https://doi.org/10.1186/s12902-023-01329-y |
||||
| Oyedeji, A. D., Ullah, I., Weich, S., Bentall, R., & Booth, A. (2022). Effectiveness of non-specialist delivered psychological interventions on glycemic control and mental health problems in individuals with type 2 diabetes: A systematic review and meta-analysis. International Journal of Mental Health Systems, 16, Article number 9. https://doi.org/10.1186/s13033-022-00521-2 |
||||
| Pan American Health Organisation (2023). Enfermedades no transmisibles [Internet]. Retrieved from https://www.paho.org/ es/temas/enfermedades-no-transmisibles. | ||||
| Presley, C., Agne, A., Shelton, T., Oster, R., & Cherrington, A. (2020). Mobile-enhanced peer support for African Americans with type 2 diabetes: a randomised controlled trial. Journal of General Internal Medicine, 35, 2889-2896. https://doi.org/10.1007/s11606-020-06011-w |
||||
| Romero Guevara, S. L., Parra, D. I., & Rojas, L. Z. (2019). " Teaching: Individual" to increase adherence to therapeutic regimen in people with hypertension and type-2 diabetes: protocol of the controlled clinical trial ENURSIN. BMC Nursing, 18, 1-9. https://doi.org/10.1186/s12912-019-0344-0 |
||||
| Romero-Castillo, R., Pabón-Carrasco, M., Jiménez-Picón, N., & Ponce-Blandón, J. A. (2022, July). Diabetes management after a therapeutic education program: a qualitative study. In Healthcare (Vol. 10, No. 8, p. 1375). MDPI. https://doi.org/10.3390/healthcare10081375 |
||||
| Sabina, J. B. (2019). Effectiveness of educational intervention on diabetic knowledge & Hba1c levels on Kenyan adults with T2DM. Doctor of Nursing Practice Projects 6. Retrieved from https://digitalcommons.andrews.edu/dnp/6 | ||||
| Salahshouri, A., Zamani Alavijeh, F., Mahaki, B., & Mostafavi, F. (2018). Effectiveness of educational intervention based on psychological factors on achieving health outcomes in patients with type 2 diabetes. Diabetology & Metabolic Syndrome, 10, Article number 67. https://doi.org/10.1186/s13098-018-0368-8 |
||||
| Sheikhi, H. R., Heydari, M. A., Soleimani, M., Sheikhi, A. R., Mastaelizadeh, H., & Naderyanfar, F. (2019). The effect of family-centered education on self-care rate in patients with type 2 diabetes. Journal of Advanced Pharmacy Education and Research, 9, 55-63. | ||||
| Stapleton, C., Watkins, E., Hare, M. J., Timms, F., Wood, A. J., & Titmuss, A. (2022). The prevalence of diabetes distress and its association with glycaemia in young people living with insulin‐requiring‐diabetes in a regional centre in Australia. Journal of Paediatrics and Child Health, 58(12), 2273-2279. https://doi.org/10.1111/jpc.16221 |
||||
| Tricco, A. C., Lillie, E., Zarin, W., O'Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M.D., Horsley, T., Weeks, L., & Straus, S. E. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Annals of Internal Medicine, 169(7), 467-473. https://doi.org/10.7326/M18-0850 |
||||
| Vacurova, E., Trnovska, J., Svoboda, P., Skop, V., Novosadova, V., Reguera, D. P., Petrezselyová, S., Piavaux, B., Endaya, B., Spoutil, F., Zudova, D., Stursa, J., Melcova, M., Bielcikova, Z., Werner, L., Prochazka, J., Sedlacek, R., Huttl, M., Hubackova, S. S., Haluzik, M., & Neuzil, J. (2022). Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice. Nature Communications, 13 Article number, 1866. https://doi.org/10.1038/s41467-022-29486-z |
||||
| Van Nguyen, T., Wantonoro, W., & Suryaningsih, E. K. (2021). Self-management behavior interventions for type 2 diabetes mellitus: A Review. Open Access Macedonian Journal of Medical Sciences, 9(F), 556-562. https://doi.org/10.3889/oamjms.2021.7446 |
||||
| Wang, X., Wang, K., Huang, K., Wu, X., Huang, W., & Yang, L. (2021). The association between demographic characteristics, personality, and mental health of bus drivers in China: A structural equation model. Physiology & Behaviour, 229, Article number 113247. https://doi.org/10.1016/j.physbeh.2020.113247 |
||||
| White, R. O., Chakkalakal, R. J., Wallston, K. A., Wolff, K., Gregory, B., Davis, D., Schlundt, D., Trochez, K. M., Barto, S., Harris, L. A., & Rothman, R. L. (2020). The Partnership to Improve Diabetes Education Trial: a cluster randomised trial addressing health communication in diabetes care. Journal of General Internal Medicine, 35(4), 1052-1059. https://doi.org/10.1007/s11606-019-05617-z |
||||
| World Health Organisation (WHO) (2022). Fact sheet: Dementia. Retrieved from https://www.who.int/news-room/fact-sheets/detail/dementia | ||||
| Xiong, Y., Chen, X., Zhao, X., Fan, Y., Zhang, Q., & Zhu, W. (2020). Altered regional homogeneity and functional brain networks in Type 2 diabetes with and without mild cognitive impairment. Scientific Reports, 10(1), 21254. https://doi.org/10.1038/s41598-020-76495-3 |
||||
| Zhou, B., Wang, X., Yang, Q., Wu, F., Tang, L., Wang, J., & Li, C. (2022). Topological alterations of the brain functional network in type 2 diabetes mellitus patients with and without mild cognitive impairment. Frontiers in Aging Neuroscience, 14, Article number 834319. https://doi.org/10.3389/fnagi.2022.834319 |
||||