JOURNAL OF ANIMAL SCIENCE AND VETERINARY MEDICINE
Integrity Research Journals
ISSN: 2536-7099
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASVM
Start Year: 2016
Email: jasvm@integrityresjournals.org
Evaluation of haematology, serum biochemistry and immune competence of broiler chickens supplemented with dietary zinc and selenium nanoparticles
https://doi.org/10.31248/JASVM2024.505 | Article Number: 93D7673011 | Vol.9 (6) - December 2024
Received Date: 06 November 2024 | Accepted Date: 20 December 2024 | Published Date: 30 December 2024
Authors: Sa’aci, Z. A.* , Alabi, O. J. , Jiya, E. Z. , Ijaiya, A. T. , Mbajiorgu E. F. and Egwim, E. C.
Keywords: haematology, Broiler chickens, immune competence, nano zinc, selenium, serum biochemical profile
The study evaluated the effect of dietary supplementation of nano zinc and selenium on haematology, serum biochemical parameters and immune function of broiler chickens. Seven hundred and sixty-eight (768) one-day-old Arbor acre broiler chicks were arranged in a 4 × 4 factorial layout in a Completely Randomized Design based on dietary zinc and selenium nanoparticles into sixteen treatments consisting of four replicates with 12 birds per replicate for an experimental duration of 29 days. Birds were reared on deep litter and fed basal diets enriched with four levels of nano zinc (20, 30, 40 and 50 mg/kg NZn) and four levels of nano selenium (0.10, 0.15, 0.20 and 0.25 mg/kg NSe). On day 49, blood samples were collected from two randomly selected birds in each replicate to determine haematology, serum biochemical profile and immunoglobulin concentrations. Data generated were subjected to a two-way analysis of variance using the General Linear Model of Statistical Package for Social Science (SPSS version 16.0). Results indicated haemoglobin, PCV, RBC, neutrophils, lymphocytes and glucose, urea creatinine, cholesterol, albumin, nitrogen, aspartate amino transaminase and alkaline phosphatase were significantly (p<0.05) improved by 50 mg of Zn/kg with 0.15 mg of Se/kg and their values are within the range of reference values. Birds fed up to 50 mg/kg NZn revealed enhanced thymus, bursa of Fabricius, spleen and IgM. Similarly, 0.10 to 0.25 mg/kg NSe improved the bursa of Fabricius, IgA, IgG and IgM. Dietary supplementation of nano zinc and selenium improved blood biochemical parameters and increased immunity without any detrimental effect on the birds’ health.
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