JOURNAL OF ANIMAL SCIENCE AND VETERINARY MEDICINE
Integrity Research Journals
ISSN: 2536-7099
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASVM
Start Year: 2016
Email: jasvm@integrityresjournals.org
Lymphangiomatosis in the oral cavity in a mix breed dog
https://doi.org/10.31248/JASVM2024.495 | Article Number: 33D03A4D2 | Vol.9 (6) - December 2024
Received Date: 18 October 2024 | Accepted Date: 20 November 2024 | Published Date: 30 December 2024
Authors: Cesar Vega* , Jamie G. Anderson and Judy Force
Keywords: Canine, Lymphangiomatosis, tongue, mouth, oral medicine.
A 12-year-old female spayed mixed breed dog presented with numerous firm proliferating, non-painful white/tan lesions on both the dorsal and ventral surface of the tongue. Initial clinical differentials include trauma, infection, and cancer. Histopathology revealed multifocal fibroangiomatous mucosal hyperplasia with foamy macrophages. Differential diagnoses included histiocytic foam cell nodules, xanthogranuloma (lipid-rich granuloma) or foam cell nodules containing lipid, cutaneous foam cell histiocytosis affecting the oral cavity, or systemic histiocytosis. Due to the presence of multiple lesions, medical therapy with tetracycline, and niacinamide was initiated, resulting in clinical improvement. Subsequent immunohistochemical staining identified branching and connecting CD31+ lymphatics throughout the sample, suggesting lymphagiomatosis. Lymphagiomatosis is an infiltrative disease affecting lymphatic vessels in one or multiple organs. This condition has not been previously reported in dogs. This case report is the first to describe lymphangiomatosis in a mixed-breed dog.
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