JOURNAL OF PUBLIC HEALTH AND DISEASES
Integrity Research Journals

ISSN: 2705-2214
Model: Open Access/Peer Reviewed
DOI: 10.31248/JPHD
Start Year: 2018
Email: jphd@integrityresjournals.org


A review of endemicity and control strategies against lymphatic filariasis in Nigeria

https://doi.org/10.31248/JPHD2021.101   |   Article Number: F137B8D42   |   Vol.4 (5) - December 2021

Received Date: 11 May 2021   |   Accepted Date: 08 October 2021  |   Published Date: 30 December 2021

Authors:  Luka, J. , Okeke, P. , Ombugadu, A. and Yina, G. I.*

Keywords: Control, endemic, lymphatic filariasis, MDA.

Lymphatic Filariasis (LF) is a neglected tropical disease (NTDs) that persists in developing countries causing disability through disfiguration with great economic repercussions. In Nigeria, LF is transmitted by female mosquitoes and caused by nematode, Wuchereria bancrofti. The vectors of LF, anopheles and culex mosquitoes, are widespread across rural and urban areas. This review focuses on the level of endemicity and control strategies employed against LF in Nigeria. Only reliable surveys are included in this review and criteria are applied to information identified through searches of published research in peer reviewed journals of electronic bibliographic and manual searches of local archives and libraries. Data are excluded if based on personal unpublished views. Two main strategies were employed for the control of LF as a public health problem in Nigeria, (i) interrupting transmission through annual large-scale treatment programmes, known as mass drug administration (MDA) of single doses of albendazole plus either diethylcarbamazine or ivermectin implementation to cover the entire population at risk which is not scaled up to all endemic areas and (ii) alleviating the suffering caused by LF through morbidity management and disability prevention. In Nigeria, the former has gain prominence than the latter. Despite lack of total therapeutic coverage of MDA, high success has been achieved leading to elimination of LF in some states in the country. Availability and resistance of vector species to insecticide govern transmission and sustainability of LF in Nigeria. In view to ensuring a successful control plan and eventual eradication of the disease, in addition to MDA, morbidity management and vector control to prevent human mosquitoes contact should be scale up.

Anosike, J. C., Nwoke, B. E., Ajayi, E. G., Onwuliri, C. O., Okoro, O. U., Oku, E. E., ... & Meribe, C. O. (2005). Lymphatic filariasis among the Ezza people of Ebonyi state, eastern Nigeria. Annals of Agricultural and Environmental Medicine, 12(2), 181-186.
 
Bockarie, M. J., Pedersen, E. M., White, G. B., & Michael, E. (2009). Role of vector control in the global program to eliminate lymphatic filariasis. Annual Review of Entomology, 54, 469-487.
Crossref
 
Celone, M. (2015). Barriers to the elimination of lymphatic filariasis in Sub-Saharan Africa. The Columbia University Journal of Global Health, 5(1), 26-32.
 
Center for Disease Control and Prevention (CDC) (1993). Recommendations of the International Task Force for Disease Eradication. Morbidity Mortality Weekly Report, 42(RR-16), 1-23.
Link
 
Chakraborty, S., Gurusamy, M., Zawieja, D. C., & Muthuchamy, M. (2013). Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis. Microcirculation, 20(5), 349-364.
Crossref
 
Conteh, L., Engels, T., & Molyneux, D. H. (2010). Socioeconomic aspects of neglected tropical diseases. The Lancet, 375(9710), 239-247.
Crossref
 
Dreyer, G., Norões, J., & Addiss, D. (1997). The silent burden of sexual disability associated with lymphatic filariasis. Acta Tropica, 63, 57-60.
Crossref
 
Dzodzomenyo, M., & Simonsen, P. E. (1999). Bancroftian filariasis in an irrigation project community in southern Ghana. Tropical Medicine & International Health, 4(1), 13-18.
Crossref
 
Elkanah, O. S., Elkanah, D. S., Wahedi, J. A., Kela, S. L., & Samaila, A. B. (2020). Field Comparison be-tween Blood Immunochromatographic Card Test and Microscopy in Diagnosis of Bancroftian Filariasis in Northern Taraba State, Nigeria. International Journal of Open Access Tropical Diseases, 3, Article Number 042.
Crossref
 
Eneanya, O. A., Cano, J., Dorigatti, I., Anagbogu, I., Okoronkwo, C., Garske, T., & Donnelly, C. A. (2018). Environmental suitability for lymphatic filariasis in Nigeria. Parasites & Vectors, 11, Article Number 513.
Crossref
 
Evans, D. B., Gelband, H., & Vlassoff, C. (1993). Social and economic factors and the control of lymphatic filariasis: a review. Acta Tropica, 53(1), 1-26.
Crossref
 
Famakinde, D. O. (2018). Mosquitoes and the lymphatic filarial parasites: research trends and budding roadmaps to future disease eradication. Tropical Medicine and Infectious Disease, 3, Article Number 4.
Crossref
 
Federal Ministry of Health (FMoH) (2019). Nigeria master plan for Neglected Tropical Diseases (NTDs) (2015-2020). Government of the Federal Republic of Nigeria, Abuja.
 
Gyapong, J. O., Owusu, I. O., Vroom, F. B. D. C., Mensah, E. O., & Gyapong, M. (2018). Elimination of lymphatic filariasis: current perspectives on mass drug administration. Research and Reports in Tropical Medicine, 9, 25-33.
Crossref
 
Gyapong, M., Gyapong, J., Weiss, M., & Tanner, M. (2000). The burden of hydrocele on men in Northern Ghana. Acta Tropica, 77(3), 287-294.
Crossref
 
Hotez, P. J., Asojo, O. A., & Adesina, A. M. (2012). Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. PLoS Neglected Tropical Diseases, 6(7), e1600.
Crossref
 
Hussaini, A., Isaac, C., Rahimat, H., Collins, I., Cedric, O., & Solomon, E. (2020). The Burden of Bancroftian Filariasis in Nigeria: A Review. Ethiopian journal of health sciences, 30(2), 301-310.
Crossref
 
Ichimori, K. (2014). MDA-lymphatic filariasis. Journal of Tropical Medicine and Health, 42(2), 21-24.
Crossref
 
John, D. T., & William, A. P. Jr. (2006). Medical parasitology. 9th edition. St. Louis, Missouri: Saunders Elsevier. Pp. 274-289.
 
Mackey, T. K., & Liang, B. A. (2012). Lessons from SARS and H1N1/A: employing a WHO-WTO forum to promote optimal economic-public health pandemic response. Journal of Public Health Policy, 33, 119-130.
Crossref
 
Mackey, T. K., Liang, B. A., Cuomo, R., Hafen, R., Brouwer, K. C., & Lee, D. E. (2014). Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment. Clinical Microbiology Reviews, 27(4), 949-979.
Crossref
 
Molyneux, D. (2003). Lymphatic filariasis (elephantiasis) elimination: a public health success and development opportunity. Filaria Journal, 2, Article number 13.
 
Mshana, H. J., Baraka, V., Misinzo, G., & Makunde, W. H. (2016). Current epidemiological assessment of bancroftian filariasis in Tanga region, northeastern Tanzania. Journal of Tropical Medicine, Volume 2016, Article ID 7408187, 5 pages.
Crossref
 
Nwoke, B. E. B., Nwoke, E. A., Ukaga, C. N., & Nwachukwu, M. I. (2010). Epidemiological characteristics of bancroftian filariasis and the Nigerian environment. Journal of Public Health and Epidemiology, 2(6), 113-117.
 
Obindo, J., Abdulmalik, J., Nwefoh, E., Agbir, M., Nwoga, C., Armiya'u, A., Davou, F., Maigida, K., Otache, E., Ebiloma, A., & Eaton, J. (2017). Prevalence of depression and associated clinical and socio-demographic factors in people living with lymphatic filariasis in Plateau State, Nigeria. PLoS Neglected Tropical Diseases, 11(6), e0005567.
Crossref
 
Omedo, M. O., Matey, E. J., Awiti, A., Ogutu, M., Alaii, J., Karanja, D. M., Montgomery, S. P., Secor, W. E., & Mwinzi, P. N. (2012). Community health workers' experiences and perspectives on mass drug administration for schistosomiasis control in western Kenya: the SCORE Project. The American Journal of Tropical Medicine and Hygiene, 87(6), 1065-1072.
Crossref
 
Ottesen, E. A., (2000). Editorial: the global programme to eliminate lymphatic filariasis. Journal of Tropical Medicine and International Health, 5(9), 591-594.
Crossref
 
Ottesen, E. A., Hooper, P. J., Bradley, M., & Biswas, G. (2008). The global programme to eliminate lymphatic filariasis: health impact after 8 years. PLoS Neglected Tropical Diseases, 2(10), e317.
Crossref
 
Ramaiah, K. D., & Kumar, K. V. (2000). Effect of lymphatic filariasis on school children. Acta Tropica, 76(2), 197-199.
Crossref
 
Shenoy, R. K. (2008). Clinical and pathological aspects of filarial lymphedema and its management. The Korean Journal of Parasitology, 46(3), 119-125.
Crossref
 
Shenoy, R. K., Suma, T. K., Kumaraswami, V., Rahmah, N., Dhananjayan, G., Padma, S., Abhilash, G., & Ramesh, C. (2007). Preliminary findings from a cross-sectional study on lymphatic filariasis in children, in an area of India endemic for Brugia malayi infection. Annals of Tropical Medicine & Parasitology, 101(3), 205-213.
Crossref
 
Sogoba, N., Doumbia, S., Vounatsou, P., Baber, I., Keita, M., Maiga, M., & Ribeiro, J. M. C. (2007). Monitoring of larval habitats and mosquito densities in the Sudden Savannah of Mali: Implication for malaria vector control. American Journal of Tropical Medicine and Hygiene, 77(1), 82-88.
Crossref
 
The Carter Center (2021). Lymphatic filariasis elimination program.
Link
 
Ton, T. G., Mackenzie, C., & Molyneux, D. H. (2015). The burden of mental health in lymphatic filariasis. Infectious Diseases of Poverty, 4, Article number 34.
Crossref
 
Ughasi, J., Bekard, H. E., Coulibaly, M., Adabie-Gomez, D., Gyapong, J., Appawu, M., Wilson, M. D., & Boakye, D. A. (2012). Mansonia africana and Mansonia uniformis are vectors in the transmission of Wuchereria bancrofti lymphatic filariasis in Ghana. Parasites & Vectors, 5, Article number 89.
Crossref
 
Witt, C., & Ottesen, E. A. (2001). Lymphatic filariasis: an infection of childhood. Tropical Medicine & International Health, 6(8), 582-606.
Crossref
 
World Health Organization (WHO) (2010). Progress report 2000-2009 and strategic plan 2010-2020 of the global programme to eliminate lymphatic filariasis: halfway towards eliminating lymphatic filariasis.
Link
 
World Health Organization (WHO) (2011). Monitoring and epidemiological assessment of mass drug administration in globalprogramme to eliminate lymphatic filariasis: A manual for national elimination programmes. Geneva: World Health Organization.
 
World Health Organization (WHO) (2012). Lymphatic filariasis [Fact Sheet].
Link
 
World Health Organization (WHO) (2013). Global programme to eliminate lymphatic filariasis. A Handbook of practical entomology for national lymphatic filariasis elimination programmes.
 
World Health Organization (WHO) (2014). Fact sheet, lymphatic filariasis world health day 2014.
Link
 
World Health Organization (WHO) (2017). Expanded special project for elimination of neglected tropical disease.
Link
 
World Health Organization (WHO) (2019). Lymphatic filariasis fact sheet. Retrieved from www.WHO.int/news-room/fact-sheet/detail/lymphatic-filariasis.
 
Wynd, S., Melrose, W. D., Durrheim, D. N., Carron, J., & Gyapong, M. (2007). Understanding the community impact of lymphatic filariasis: a review of the sociocultural literature. Bulletin of the World Health Organization, 85(6), 493-498.
Crossref