JOURNAL OF BIOSCIENCE AND BIOTECHNOLOGY DISCOVERY
Integrity Research Journals

ISSN: 2536-7064
Model: Open Access/Peer Reviewed
DOI: 10.31248/JBBD
Start Year: 2016
Email: jbbd@integrityresjournals.org


Epidemiology of microsporidia infection among apparently healthy subject and immunocompromised patients in Minna

https://doi.org/10.31248/JBBD2018.076   |   Article Number: 1E12B2D32   |   Vol.4 (2) - April 2019

Received Date: 13 July 2018   |   Accepted Date: 13 August 2018  |   Published Date: 30 April 2019

Authors:  Ubanwa E.* , Omalu I. C. J. , Olayemi I. K. , Ejima, I. A. A. and Njoku, M. O.

Keywords: Cytometer, immunodeficiency, immunosuppressive, microsporidia.

Microsporidia are obligate intracellular parasite that infect both vertebrate and invertebrate. In human, infection mostly focus on immunodeficiency and immunosuppressive individual. This study describes the prevalence, association of microsporidia infection with CD4 T Cell and risk factors associated with microsporidiosis among apparently health subject and immunocompromised individual in Minna, Niger state, Nigeria. Six hundred and Ninety-four (694) stools samples were collected and examined for microsporidia using Giemsa staining. Cytometer flow was used to determine CD4 T cell count. Pretest questionnaire was used to determine demographic, environmental hygiene, living condition and characteristics of the participants. Results showed 42 (6.06%) of the participant with and without diarrhoeawere positive for microsporidia infection. Histogram were used to describe distribution of microsporidia infection across diseases state. With cytometer flow, 6 (33.3%) among HIV/AIDS with ≤ 50 cell/µl. Highest prevalence were recorded among age ≥ 15 when compare with < 15 with 32 (10.8%) and 10 (7.47%), respectively. This study is first report of microsporidia in Niger state. Diagnose of microsporidia should be included in management of HIV/AIDS infection in Niger state.

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