Journal of Bioscience and Biotechnology Discovery

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JOURNAL OF BIOSCIENCE AND BIOTECHNOLOGY DISCOVERY
Integrity Research Journals

ISSN: 2536-7064
Model: Open Access/Peer Reviewed
DOI: 10.31248/JBBD
Start Year: 2016
Email: jbbd@integrityresjournals.org

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JBBD Articles

Evaluating The Effectiveness Of Kitchen Waste Compost Through Soil Quality Indicators, Nutrient Status, And Bacterial Diversity Using Lettuce (lactuca Sativa) Growth As A Bioassay
Authors:  Nyandjou, Yomi Marie Carole*, Okoye Rosemary and Oluchukwu Abba
https://doi.org/10.31248/JBBD2025.245   |   Article Number: F3EF1B2C1
The challenge of managing burgeoning kitchen waste requires sustainable valorisation methods, with composting representing a solution for producing beneficial soil amendment. This study assessed the efficacy of locally-sourced compost against conventional chemical fertiliser and unamended soil based on its impact on soil characteristics and the subsequent growth... Continue here
Synergistic Antibacterial Effect Of Adenodolichos Paniculatus Root Bioactive Fraction And Cefotaxime Against Esbl-producing Enterobacteriaceae
Authors:  Kyahar, I. F.* and Aboh, I. M.
https://doi.org/10.31248/JBBD2026.250   |   Article Number: 6C2396872
The emergence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae has reduced the clinical effectiveness of third-generation cephalosporins. This study investigated the synergistic antibacterial potential of the root bioactive component of Adenodolichos paniculatus combined with cefotaxime against ESBL-producing Enterobacteriaceae. The plant... Continue here
Fermentation Of Tiger Nut Milk Using Lactobacillus Plantarum: An Implication For Aflatoxin Reduction
Authors:  Ogunkanmi, J. O.*, Mabadeje, O. I., Alfred, M. O., Adeleye, T. M., Oni, E. O., Kajihausa, O. E. and Afolabi, O. R.
https://doi.org/10.31248/JBBD2026.249   |   Article Number: 7B22CDD13
Tiger nut (Cyperus esculentus) is a spherical rhizome crop that can be eaten raw, dried or processed. The study aims at examining the effects of fermentation on aflatoxins present in tiger nuts (Cyperus esculentus (L) milk using lactic acid bacteria. This study enumerated microorganisms in tiger nut milk during fermentation using standard microbiological methods.... Continue here
In Vitro Anti-trypanosomal Activity Of Thysanophora Penicilloides, Aureobasdium Pullulans, And Sporangia Spp Extracts
Authors:  Tukur, S. T.*, Jega, Y. N. and Faragai, S. R.
https://doi.org/10.31248/JBBD2026.253   |   Article Number: 89730E261
The genus Trypanosoma, a flagellated protozoan, causes trypanosomiasis. The disease occurs in humans and animals in Africa and South America. African trypanosomiasis is a debilitating disease affecting humans and domestic animals in the humid and sub-humid zones of Africa. It's estimated that over 60 million people and 50 -70 million animals are exposed to the... Continue here
Bacteriological And Physicochemical Changes Of Automobile Workshop Contaminated Soil Amended With Fish Pond Sludge: A Bioremediation Study From Lokoja, Nigeria
Authors:  Amupitan, P., Maji, E. A., Ocean, H. O. and Stephen, E.*
https://doi.org/10.31248/JBBD2026.254   |   Article Number: ED4071D42
The bacteriological and physicochemical changes of automobile workshop polluted soil in Lokoja, Kogi State, Nigeria, amended with varying concentrations of fish pond sludge (10%, 20% and 40%) was studied for six months. The bacteria population was assessed using serial dilution and plate counts after 24 hours of incubation on nutrient agar. Pure isolates were... Continue here
Bioassay-driven Fractionation And In Vivo Evaluation Of Hepatoprotective Potentials Of Gymnema Sylvestre Methanolic Leaf Extract In Wistar Albino Rat
Authors:  Kabiru Usman*, Umar Adamu, A.b. Hamza, Muttaka Auwalu, Mansur Usman, A.a. Naibi, N. I. Danmaliki, Nafiu Bello, Abubakar Yusuf, Aliyu Garba and Sambo A. Sambo
https://doi.org/10.31248/JBBD2026.251   |   Article Number: 629C4F6A3
This study was conducted to assess the hepatoprotective potential of Gymnema sylvestre methanolic leaf extract through bioactivity-guided fractionation with Wistar albino rats induced with Carbon tetrachloride (CCl4). Study of qualitative phytochemical analysis performed on the extract revealed the presence of flavonoids, saponins, alkaloids, steroids, tannins,... Continue here
Anticancer Potentials Of Medicinal Plants: Phytochemicals, Molecular Mechanisms, And Plant-mediated Sulfur Nanoparticles
Authors:  Kabiru Usman*, Muhammad Abdullahi, A. B. Hamza, Mansur Usman, A. A. Na’ibi, N.i. Danmaliki, Muzakkir Bello, Umar Adamu, Nafiu Bello, Aliyu Garba and Abubakar Yusuf
https://doi.org/10.31248/JBBD2026.255   |   Article Number: 18A694FB4
Despite advances in oncology, cancer treatment remains limited by therapeutic resistance, toxicity, and high treatment costs. Natural products, particularly plant-derived secondary metabolites, have historically contributed to the discovery of several clinically approved anticancer drugs and continue to represent an important source of new therapeutic leads. In... Continue here
Experimental Investigation Of The Viability Of Biodiesel Synthesized From Moringa Seed Oil In Oil Based Drilling Mud Formulation
Authors:  Obeta, P. O.* and Edo-osagie, O. S.
https://doi.org/10.31248/JBBD2026.259   |   Article Number: 6269A6FD5
The environmental and regulatory pressures associated with petroleum diesel‑based drilling fluids have accelerated the search for sustainable alternatives in oil and gas operations. This study evaluates Moringa oleifera seed oil biodiesel as a substitute base fluid in oil‑based mud (OBM) formulations. Moringa seeds were sourced locally in Lagos, Nigeria, prepared... Continue here
Evaluation Of Antiplasmodial Activities And Synergistic Interactions Of Quinine With Root Extract Of Nauclea Latifolia Against Plasmodium Falciparum
Authors:  Kyahar, I. F.* and Aboh, I. M.
https://doi.org/10.31248/JBBD2026.260   |   Article Number: 5C8B8C9F1
Nauclea latifolia is widely used in African traditional medicine for malaria, yet systematic evaluation of its antiplasmodial activity and pharmacodynamic interactions with standard drugs remains limited. This study investigated the in vitro antiplasmodial activity, cytotoxicity, and interaction of the methanol root extract of N. latifolia with quinine. The... Continue here
Prevalence Of Parasitic Infections In Slaughtered Cattle From Selected Abattoirs In South Eastern States Of Nigeria
Authors:  Nwadike, C. C., Ezeagwuna, D. A., Ogbuefi, E. O., Obiefule, I. E.2, Nnatuanya, I. O., Okeke, O. A. and Amaechi, E. C.
https://doi.org/10.31248/JBBD2026.261   |   Article Number: E54958AC2
Cattle production is greatly constrained by parasitic infection, which hampers its welfare and productivity and poses a serious public health concern to the general populace. This study investigates the various cattle parasites and other study parameters. A total of eighty (80) faecal and blood samples were collected from cattle at selected abattoirs in both... Continue here
Toxicity Evaluation Of The Fruit Peel Extract Of Cucumis Metuliferus In Wistar Rats
Authors:  Ruth N. Doeka’at*, Noel N. Wannang and John C. Aguiyi
https://doi.org/10.31248/JBBD2026.264   |   Article Number: 5D5083043
Cucumis metuliferus is a commonly used medicinal herb in traditional medicine. Recent investigations showed that the peel of Cucumis metuliferus fruit contains numerous bioactive components and remains largely unexplored in terms of its bioactive potential and safety profile. Through phytochemical screening and acute, sub-acute (28-day), and sub-chronic (90-day)... Continue here
Sedative Responses Of Clarias Gariepinus And Heterobranchus Longifilis Broodstocks To Lime (citrus Aurantiifolia) Leaf Extract After Stripping And During Transportation
Authors:  Robert, E. A.*, Yem, I. Y., Landu, E. J., Gwari, B. M., Ogbuebunu, K. E., Manuwuike, Q. M. and Owolabi, E. S.
https://doi.org/10.31248/JBBD2026.265   |   Article Number: 6C86021B4
Handling catfish properly has precipitated the use of anaesthesia to minimise stress and prevent injuries. This study aims to show the efficacy of lime leaf extract as a sedative for Clarias gariepinus and Heterobranchus longifilis female broodstocks, after stripping and during transportation of broodfish to a fish farm in New Bussa. A total of 48 female... Continue here

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