JOURNAL OF AGRICULTURAL SCIENCE AND PRACTICE
Integrity Research Journals

ISSN: 2536-7072
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASP
Start Year: 2016
Email: jasp@integrityresjournals.org


Effect of secondary compounds on nutrients utilization and productivity of ruminant animals: A review

https://doi.org/10.31248/JASP2018.096   |   Article Number: ACC0046B8   |   Vol.5 (1) - February 2020

Received Date: 24 May 2018   |   Accepted Date: 27 September 2018  |   Published Date: 28 February 2020

Authors:  Hussen Ebrahim* and Fasil Negussie

Keywords: ruminants, Flavoids, saponins, secondary compounds, tannins.

Plants produce secondary compounds (include tannins, saponins, flavoids, glucosinolates, mimosine and essential oils) which are not used for their growth, development and reproduction of the plant. The review found out the nutrient utilization and productivity performance of ruminant animals supplementing with secondary compounds containing forages, browse species, shrubs, grains, legumes and others. Secondary compounds influence the digestibility, dry matter intake and absorption of nutrients in ruminant’s nutrition. Their dose determines whether they are enhancers or detrimental. Tannins, saponins and essential oils are the major secondary compounds which may improve the health, average live weight gain and milk and wool production. Moreover, ruminant animals consuming secondary compound containing forages support the efficient utilization of energy while reducing the rumen gas production which results in low methane. The main problem of supplementing such kind of forages is the absence of consistent recommended dose. Therefore, this area needs to get more attention and further research should be done to establish much more profitable farm and to boost the economic value of ruminant animals.

Aachary, A. A., & Thiyam, U. (2012). A pursuit of the functional nutritional and bioactive properties of canola proteins and peptides. Critical Reviews in Food Science and Nutrition, 52(11), 965-979.
Crossref
 
Addisu, S. (2016). Effect Of Dietary Tannin Source Feeds On Ruminal Fermentation And Production Of Cattle; A Review. Online Journal of Animal and Feed Research, 6(2), 45-56.
 
Agrawal, D. K., & Kamra, D. N. (2010, November). Global warming: Role of livestock and mitigation strategies. In International conference on "Physiological capacity building in livestock under changing climate scenario". Physiology and Climatology division, Indian Veterinary Research Institute, Izatnagar (Vol. 243122, pp. 73-80).
 
Al-Jumaili, W. S., Goh, Y. M., Jafari, S., Rajion, M. A., Jahromi, M. F., & Ebrahimi, M. (2017). An in vitro study on the ability of tannic acid to inhibit methanogenesis and biohydrogenation of C18 PUFA in the rumen of goats. Annals of Animal Science, 17(2), 491-502.
Crossref
 
Anantasook, N., Wanapat, M., Cherdthong, A., & Gunun, P. (2013). Effect of plants containing secondary compounds with palm oil on feed intake, digestibility, microbial protein synthesis and microbial population in dairy cows. Asian-Australasian Journal of Animal Sciences, 26(6), 820-826.
Crossref
 
Arjona-Alcocer, V. A., Ruiz-González, A., BriceñoPoot, E., Ayala-Burgos, A., Ruz-Ruiz, N., & Ku-Vera, J. C. (2012). Voluntary intake, apparent digestibility and blood urea levels in hair sheep fed Cynodon nlemfuensis grass mixed with Leucaena leucocephala and supplemented with rumen fermentable energy. Journal of Animal Science, 90, 125.
 
Atiku, A., Oladipo, O. O., Forcados, G. E., Usman, A. S., & Mancha, M. D. (2016). Anti-nutritional and phytochemical profile of some plants grazed upon by ruminants in North Central Nigeria during the dry season (January to April). International Journal of Livestock Production, 7(4), 19-23.
Crossref
 
Attia, M. F. A., Nour El-Din, A. N. M., El-Zarkouny, S. Z., El-Zaiat, H. M., M. M., & Sallam, S. M. A. (2016). Impact of Quebracho Tannins supplementation on productive and reproductive efficiency of dairy cows. Journal of Animal Sciences, 6, 269-288.
Crossref
 
Balcells, J., Aris, A., Serrano, A., Seradj, A. R., Crespo, J., & Devant, M. (2012). Effects of an extract of plant flavonoids (Bioflavex) on rumen fermentation and performance in heifers fed high-concentrate diets. Journal of animal science, 90(13), 4975-4984.
Crossref
 
Barros-Rodríguez, M., Solorio-Sánchez, J., Ku-Vera, J. C., Ayala-Burgos, A., Sandoval-Castro, C., & Solís-Pérez, G. (2012). Productive performance and urinary excretion of mimosine metabolites by hair sheep grazing in a silvopastoral system with high densities of Leucaena leucocephala. Tropical Animal Health and Production 44, 1873-1878.
Crossref
 
Benchaar, C., Calsamiglia, S., Chaves, A. V., Fraser, G.R., Colombatto, D., McAllister, T. A., & Beauchemin, K. A. (2008). A review of Plant-Derived Essential Oils in Ruminant Nutrition and Production. Animal Feed Science and Technology, 145, 209-228.
Crossref
 
Berdal, K. G. (2010). The importance of genetic modification for contents of bioactive compounds in feed and food plants. In: Bernhoft, A. (ed.). Bioactive compounds in plants - benefits and risks for man and animals. Oslo: The Norwegian Academy of Science and Letters, Pp. 223-235.
 
Bernhoft, A., (2010). A Brief Review on Bioactive Compounds in Plants. In: Bernhoft, A. (ed.). Bioactive compounds in plants-benefits and risks for man and animals. Oslo: The Norwegian Academy of Science and Letters, Pp. 11-17.
 
Bhatta, R., Baruah, L., Saravanan, M., Suresh, K. P., & Sampath, K. T. (2013a). Effect of tannins from medicinal and aromatic plants on rumen fermentation, protozoa population and ethanogenesis in vitro. Journal of Animal Physiology and Animal Nutrition, 97, 446-456.
Crossref
 
Bhatta, R., Saravanan, M., Baruah, L., Sampath, K. T., & Prasad, C. S. (2013b). Effect of plant secondary compounds on in vitro methane, ammonia production and ruminal protozoa population. Journal of Applied Microbiology, 115(2), 455-465.
Crossref
 
Bodas, R., Prieto, N., García-González, R., Andrés, S., Giráldez, F. J., & López, S. (2012). Manipulation of rumen fermentation and methane production with plant secondary metabolites. Animal Feed Science and Technology, 176(1-4), 78-93.
Crossref
 
Brunsvig, B. R., Smart, A. J., Bailey, E. A., Wright, C. L., Grings, E. E., & Brake, D. W. (2017). Effect of stocking density on performance, diet selection, total-tract digestion, and nitrogen balance among heifers grazing cool-season annual forages. Journal of Animal Science, 95(8), 3513-3522.
Crossref
 
Brus, M., Mergeduš, A., Povše, M. P. And Janžekovič, M. (2017). Better Tolerance Against Dietary Mycotoxins in Fattening Bulls When Supplemented With Farmatan-D. Agriculturae Conspectus Scientifcus , 82, 303-306.
 
Buccioni, A., Pauselli, M., Viti, C., Minieri, S., Pallara, G., Roscini, V., Rapaccini, S., Trabalz, M., Marinucci, P., Conte, G., & Mele, M. (2015). Milk fatty acid composition, rumen microbial population, and animal performances in response to diets rich in linoleic acid supplemented with chestnut or quebracho tannins in dairy ewes. Journal of Dairy Science, 98(2), 1145-1156.
Crossref
 
Burke, J. M., Miller, J. E., Mosjidis, J. A., & Terrill, T. H. (2012). Grazing sericea lespedeza for control of gastrointestinal nematodes in lambs. Veterinary Parasitology, 186, 507-512.
Crossref
 
Caloni, F., & Cortinovis, C. (2015). Plants poisonous to animals in Europe. Equine Veterinary Education, 27, 269-274.
Crossref
 
Castillejos, L., Calsamiglia, S., Martin-Tereso, J., & Ter Wijlen, H. (2008). In vitro evaluation of effects of ten essential oils at three doses on ruminal fermentation of high concentrate feedlot-type diets. Animal Feed Science and Technology, 145(1-4), 259-270.
Crossref
 
Chanthakhoun, V., Wanapat, M., Wachirapakorn, C. and Wanapat, S. (2011). Effect of Legume (Phaseolus Calcaratus) Hay supplementation on rumen microorganisms, fermentation and nutrient digestibility in swamp buffalo. Livestock Science, 140, 17-23.
Crossref
 
Chen, D., Chen, X., & Tu, Y. (2015). Effects of Mulberry Leaf Flavonoid and Resveratrol on Methane Emission and Nutrient Digestion in Sheep. Animal Nutrition, 1, 362-367.
Crossref
 
Chentli, A., Gillmann, L., Bouazza, L., Medjkal, S., Limami, A., Le Paven, M., & Bousseboua, H. (2014). Effects of secondary compounds from Cactus and Acacias trees on rumen microbial profile changes performed by real-time PCR. International Journal of Advanced Research, 12, 660-671.
 
Cobellis, G., Trabalza-Marinucci, M., & Yu, Z. (2016). Critical evaluation of essential oils as rumen modifiers in ruminant nutrition: A review. Science of the Total Environment, 545, 556-568.
Crossref
 
Cortés, J. E., Moreno, B., Pabón, M. L., Avila, P., Kreuzer, M., Hess, H. D., & Carulla, J. E. (2009). Effects of purified condensed tannins extracted from Calliandra, Flemingia and Leucaena on ruminal and postruminal degradation of soybean meal as estimated in vitro. Animal feed science and technology, 151(3-4), 194-204.
Crossref
 
Cortinovis, C., & Caloni, F. (2015). Alkaloid-Containing Plants Poisonous to Cattle and Horses in Europe. Toxins, 7, 5301-5307.
Crossref
 
Dalzell, S. A., Burnett, D. J., Dowsett, J. E., Forbes, V. E., & Shelton, H. M. (2012). Prevalence of mimosine and DHP toxicity in cattle grazing Leucaena leucocephala pastures in queensland, Australia. Animal Production Science, 52, 365-372.
Crossref
 
Demirtaş, A., Öztürk, H., & Pişkin, I. (2018). Overview of plant extracts and plant secondary metabolites as alternatives to antibiotics for modification of ruminal fermentation. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 65(2), 213-217.
Crossref
 
Derix, J., (2017). The Effect of high tannin concentrations in feed on protein digestion: Grazers versus intermediate browsers. Ghent: Ghent University.
 
Distel, R. A., & Villalba, J. J. (2018). Use of unpalatable forages by ruminants: The Influence of experience with the biophysical and social environment. Animals, 8(4), 15p.
Crossref
 
Durge, S. M., Tripathi, M. K., Tripathi, P., Dutta, N., Rout, P. K., & Chaudhary, U. B. (2014). Intake, nutrient utilization, rumen fermentation, microbial hydrolytic enzymes and hemato-biochemical attributes of lactating goats fed concentrate containing Brassica juncea oil meal. Small Ruminant Research, 121(2-3), 300-307.
Crossref
 
Durmic, Z., Hutton, P., Banik, B., Vadhanabhuti, J., Erskine, W., Revell, C., Ramirez-Restepo, C., & Vercoe, P. (2017). Harnessing plant bioactivity for improved ruminant production, health and methane mitigation in Australia.
 
Ehsen, S., Qasim, M., Abideen, Z. A. I. N. U. L., Rizvi, R. F., Gul, B., Ansari, R., & Khan, M. A. (2016). Secondary metabolites as anti-nutritional factors in locally used halophytic forage/fodder. Pakistan Journal of Botany, 48(2), 629-636.
 
El Shaer, H. M. (2010). Halophytes and salt-tolerant plants as potential forage for ruminants in the near East Region. Small Ruminant Research, 91(1), 3-12.
Crossref
 
García, D., Wencomo, H., Gonzáles, M., Medina, M., & Cova, L. (2008). Caracterización de diez cultivares forrajeros de Leucaena leucocephala basada en la composición química y la degradabilidad ruminal. Revista MVZ Córdoba, 13(2), 1294-1303.
Crossref
 
Gemeda, B. S., & Hassen, A., (2018). The Potential of Tropical Tannin Rich Browses in Reduction of Enteric Methane. Appro Poult Dairy and Vet. Sci, p. 9.
Crossref
 
Ghani, A. A. A., Rusli, N. D., Shahudin, M. S., Goh, Y. M., Zamri-Saad, M., Hafandi, A., & Hassim, H. A. (2017). Utilisation of Oil Palm Fronds as Ruminant Feed and Its Effect on Fatty Acid Metabolism. Pertanika Journal of Tropical Agricultural Science, 40(2), 215-224.
 
Jayanegara, A., Goel, G., Makkar, H. P. S., & Becker, K. (2010). Reduction in methane emissions from ruminants by plant secondary metabolites: effects of polyphenols and saponins. Sustainable Improvement of Animal Production and Health. Food and Agriculture Organization of the United Nations (FAO), Rome, Italy, Pp. 151-157.
 
Jayanegara, A., Goel, G., Makkar, H. P., & Becker, K. (2015). Divergence between purified hydrolysable and condensed tannin effects on methane emission, rumen fermentation and microbial population in vitro. Animal Feed Science and Technology, 209, 60-68.
Crossref
 
Jayanegara, A., Leiber, F., & Kreuzer, M. (2012). Meta‐analysis of the relationship between dietary tannin level and methane formation in ruminants from in vivo and in vitro experiments. Journal of Animal Physiology and Animal Nutrition, 96(3), 365-375.
Crossref
 
Jayanegara, A., Togtokhbayar, N., Makkar, H. P., & Becker, K. (2009). Tannins determined by various methods as predictors of methane production reduction potential of plants by an in vitro rumen fermentation system. Animal Feed Science and Technology, 150(3-4), 230-237.
Crossref
 
Jiménez-Peralta, F. S., Salem, A. Z. M., Mejia-Hernández. P., GonzálezRonquillo, M., Albarrán-Portillo. B., Rojo-Rubio. R., & TinocoJaramillo, J. L. (2011). Influence of individual and mixed extracts of two tree species on in vitro gas production kinetics of high concentrate diet fed to growing lambs. Livestock Science, 136, 192-200.
Crossref
 
Juhnke, J., Miller, J., Hall, J. O., Provenza, F. D., & Villalba, J. J. (2012). Preference for condensed tannins by sheep in response to challenge infection with Haemonchus contortus. Veterinary parasitology, 188(1-2), 104-114.
Crossref
 
Kaçar, D. (2008). Screening of some plant species for their total antioxidant and antimicrobial activities. Thesis of master degree. Graduate School of Engineering and Sciences of İzmir Institute of Technology, İzmir.
 
Kang, J., Zeng, B., Tang, S., Wang, M., Han, X., Zhou, C., Yan, Q., He, Z., Liu, J. & Tan, Z. (2016). Effects of Momordica charantia Saponins on In vitro ruminal fermentation and microbial population. Asian-Australasian Journal of Animal Sciences, 29(4), 500-508.
Crossref
 
Kaur, P., Appels, R., Bayer, P. E., Keeble-Gagnere, G., Wang, J., Hirakawa, H., Shirasawa. K., Vercoe, P., Stefanova, K., Durmic, Z., Nichols, P., Revell, C., Isobe, S. N., Edwards, D., & Erskine, W. (2017). Climate clever clovers: New paradigm to reduce the environmental footprint of ruminants by breeding low methanogenic forages utilizing haplotype variation. Frontiers in Plant Science, 8, 1463.
Crossref
 
Khamisabadi, H., Kafilzadeh, F., & Charaien, B. (2016). Effect of thyme (Thymus vulgaris) or peppermint (Mentha piperita) on performance, digestibility and blood metabolites of fattening Sanjabi lambs. Biharean Biologist, 10(2), 118-122.
 
Kim, D. H., Kim, K. H., Nam, I. S., Lee, S. S., Choi, C. W., Kim, W. Y., Kwon, E. G., Lee, K. Y., Lee, M. J., & Oh, Y. K. (2013). Effect of indigenous herbs on growth, blood metabolites and carcass characteristics in the late fattening period of Hanwoo steers. Asian-Australasian Journal of Animal Sciences, 26(11), 1562-1568.
Crossref
 
Kingston-Smith, A. H., Edwards, S. J. E., Huws, S. A., Kim, E. J., & Abberto, N. M. (2010). Plant-Based Strategies towards Minimizing 'Livestock's Long Shadow'. Proceedings of the Nutrition Society, 69, 613-620.
Crossref
 
Kreuzer, M., & Soliva, C. R. (2008). Nutrition: Key to Methane Mitigation in Ruminants. Proc. Soc. Nutr. Physiol., 17, 168-171.
 
Kumar, R., Kamra, D. N., Agarwal, N., Chaudhary, L. C., & Zadbuke, S. S. (2011). Effect of tree leaves containing plant secondary metabolites on in vitro methanogenesis and fermentation of feed with buffalo rumen liquor. Animal Nutrition and Feed Technology, 11, 103-114.
 
Lowry, J. B. (2008). Trees for wood and animal production in Northern Australia. Rural Industries Research And Development Corporation, 70, 24-56.
 
Makkar, H. P. S., Norvsambuu, T., Lkhagvatseren, S., & Becker, K. (2009). Plant secondary metabolites in some medicinal plants of Mongolia used for enhancing animal health and production. Tropicultural, 27(3),159-167.
 
Mapato, C., Wanapat, M., & Cherdthong, A. (2010). Effects of urea treatment of straw and dietary level of vegetable oil on lactating dairy cows. Tropical Animal Health and Production, 42(8), 1635-1642.
Crossref
 
Mapiye, C., Chimonyo, M., Dzama, K., Strydom, P. E., & Muchenje, V. (2010). Meat quality attributes of nguni steers supplemented with Acacia karroo leaf-meal. Meat Science, 8, 621-27.
Crossref
 
Mara, F. P. O., Beauchemin, K. A., Kreuzer, M., & Mcallister, T. A. (2008). Reduction of greenhouse gas emissions of ruminants through nutritional strategies. Livestock And Global Climate Change, Pp. 40-43.
 
Marley, C. L., Fychan, R., Davies, J. W., Theobald, V. J., Scollan, N. D., Richardson, R. I., & Sanderson, R. (2018). Stability, fatty acid composition and sensory properties of the M. Longissimus muscle from beef steers grazing either Chicory/Ryegrass or Ryegrass. Animal , 12(4), 882-888.
Crossref
 
Martínez-Ortíz-de-Montellano, C., Arroyo-López, C., Fourquaux, I., Torres-Acosta, J. F. J., Sandoval-Castro, C. A., & Hoste, H. (2013). Scanning electron microscopy of Haemonchus contortus exposed to tannin-rich plants under in vivo and in vitro conditions. Experimental Parasitology, 133(3), 281-286.
Crossref
 
Mirzaei, F. (2012). Effect of herbal feed additives on performance parameters of ruminants and especially on dairy goat: a review. Int. J. Agro Vet. Med. Sci., 6, 307-331.
Crossref
 
Molina, I. C., Angarita, E. A., Mayorga, O. L., Chará, J., & Barahona-Rosales, R. (2016). Effect of Leucaena leucocephala on methane production of Lucerna heifers fed a diet based on Cynodon plectostachyus. Livestock Science, 185, 24-29.
Crossref
 
Morales, R., & Ungerfeld, E. M. (2015). Use of tannins to improve fatty acids profle of meat and milk quality in ruminants: A review. Chilean Journal Of Agricultural Research, 75(2), 239-248.
Crossref
 
Myint, K. H., Mu, K. S., Soe, T. M., Maw, N. N., Gawng, L. M., & Ngwe, T. (2010). Evaluation of Leucaena leucocephala and Ziziphus mauritiana as Sources of Tannins and their Interference with Nitrogen Utilisation in Goats. Sustainable Improvement of animal Production and health. Food and Agriculture organization of the United Nations, Rome, 159-166.
 
Niderkor, N. V., Mueller-Harve, Y. I., Lemorva, N. A., & Aufrer, J. (2012). Synergistic effects of mixing cocksfoot and sainfoin on in vitro rumen fermentation. Role of condensed tannins. Animal Feed Science and Technology, 178, 48-56.
Crossref
 
Njidda, A. A. (2010). Chemical composition, fibre fraction and anti-nutritional substances of semi-arid browse forages of North-Eastern Nigeria. Nigerian Journal of Basic and Applied Sciences, 18(2), 181-188.
Crossref
 
Otaru, S. M., Adamu, A. M., Ehoche, O. W., & Makun, H. J. (2011). Effects of varying the level of palm oil on feed intake, milk yield and composition and postpartum weight changes of Red Sokoto goats. Small Ruminant Research, 96(1), 25-35.
Crossref
 
Patra, A. K., & Saxena, J. (2009). The effect and mode of action of saponins on the microbial populations and fermentation in the rumen and ruminant production. Nutrition Research Reviews, 22(2), 204-219.
Crossref
 
Patra, A. K., & Yu, Z. (2012). Effects of essential oils on methane production and fermentation by, and abundance and diversity of, rumen microbial populations. Applied and Environmental Microbiology, 78(12), 4271-4280.
Crossref
 
Pawar, M. M., Kamra, D. N., Agarwal, N., & Chaudhary, L. C. (2014). Effects of essential oils on in vitro methanogenesis and feed fermentation with buffalo rumen liquor. Agricultural Research, 3(1), 67-74.
Crossref
 
Piluzza, G., Sullas, L., & Bullitta, A. (2014) Tannins in forage plants and their role in animal husbandry and environmental sustainability: A Review. Grass and Forage Science, 69, 32-48.
Crossref
 
Ramírez-Restrepo, C. A., Tan, C., López-Villalobos, N., Padmanabha, J., Wang, J., & McSweeney, C. S. (2016). Methane production, fermentation characteristics, and microbial profiles in the rumen of tropical cattle fed tea seed saponin supplementation. Animal Feed Science and Technology, 216, 58-67.
Crossref
 
Ruz-Ruiz, N. E. (2013). Urinary excretion of metabolites of Mimosine (3,4-DHP and 2,3- DHP) in cattle fed different levels of Leucaena leucocephala. Msc. Thesis. University of Yucatan, Mexico. (In Spanish).
 
Salem, A. Z. M., Hassan, A. A., Khalil, M. S., Gado, H. M., Alsersy, H., & Simbaya, J. (2012). Effects of sun-drying and exogenous enzymes on nutrients intake, digestibility and nitrogen utilization in sheep fed Atriplex halimus foliages. Animal Feed Science and Technology, 171(2-4), 128-135.
Crossref
 
Seradj, A. R. (2015). Study the effect of inclusion of feed flavonoid substances on animal performance and ruminal fermentation in calves (Doctoral dissertation, Universitat de Lleida).
 
Seradj, A. R., Abecia, L., Crespo, J., Villalba, D., Fondevila, M., & Balcells, J. (2014). The effect of Bioflavex® and its pure flavonoid components on in vitro fermentation parameters and methane production in rumen fluid from steers given high concentrate diets. Animal Feed Science and Technology, 197, 85-91.
Crossref
 
Shereef, A. A. E. (2016). Kochia plant as potential forage for ruminants under desert conditions. Annual Research and Review In Biology, 10,1-6.
Crossref
 
Sikosana, J. L. N., Smith, T., Sisito, G., & Malaba, G. (2008). The nutrient degradability of Acacia nilotica pods offered to indigenous goats after mixing with wood ash or polyethylene glycol. Livestock and Climate Change, Pp. 147-149.
 
Sun, X. Z., Waghorn, G. C., Hoskin, S. O., Harrison, S. J., Muetzel, S., & Pacheco, D. (2012). Methane emissions from sheep fed fresh brassicas (Brassica spp.) compared to perennial ryegrass (Lolium perenne). Animal Feed Science and Technology, 176(1-4), 107-116.
Crossref
 
Szumacher-Strabel, M., & Cieślak, A. (2010). Potential of phytofactors to mitigate rumen ammonia and methane production. Journal of Animal and Feed Science, 19(3), 319-337.
Crossref
 
Tanwar, P. S., Rathore, S. S., & Kumar, Y. (2008). Effect of shatavari (Asparagus recemosus) on milk production in dairy animals. Indian Journal of Animal Research, 42(3), 232-233.
 
The University of California Division of Agriculture and Natural Resource (ANR). (2015). Cattle, sheep, goats and horses. What is the diffrence for working the rangeland, California: Understanding Working Rangelands.
 
Tripathi, M. K., & AS, M. (2017). Prospects and problems of dietary glucosinolates in animal feeding. Advances In Dairy Research, 5(3), 5.
Crossref
 
Vasta, V., Nudda, A., Cannas, A., Lanza, M., & Priolo, A. (2008). Alternative feed resources and their effects on the quality of meat and milk from small ruminants. Animal Feed Science and Technology, 147(1-3), 223-246.
Crossref
 
Verstraete, F. (2010). Management and regulation of certain bioactive compounds present as inherent toxins in plants intended for feed and food. In: A. Bernhoft (Ed.). Bioactive compounds in plants - Benefits and risks for man and animals. Oslo: The Norwegian Academy of Science and Letters. Pp.159-191.
 
Waghorn, G. (2008). Beneficial and detrimental effects of dietary condensed tannins for sustainable sheep and goat production progress and challenges. Animal Feed Science And Technology, 147, 116-139.
Crossref
 
Wanapat, M., Kang, S., Khejornsart, P., & Wanapat, S. (2013). Effects of plant herb combination supplementation on rumen fermentation and nutrient digestibility in beef cattle. Asian-Australasian Journal of Animal Sciences, 26(8), 1127-1136.
Crossref
 
Wanapat, M., Mapato, C., Pilajun, R., & Toburan, W. (2011). Effects of vegetable oil supplementation on feed intake, rumen fermentation, growth performance, and carcass characteristic of growing swamp buffaloes. Livestock Science, 135(1), 32-37.
Crossref
 
Wang, J. K., Ye, J. A., & Liu, J. X. (2012). Effects of tea saponins on rumen microbiota, rumen fermentation, methane production and growth performance - A review. Tropical Animal Health and Production, 44(4), 697-706.
Crossref
 
Weyl-Feinstein, S., Markovics, A., Eitam, H., Orlov, A., Yishay, M., Agmon, R., Miron, J., Izhaki, I., & Shabtay, A. (2014). Effect of pomegranate-residue supplement on Cryptosporidium parvum oocyst shedding in neonatal calves. Journal of Dairy Science, 97(9), 5800-5805.
Crossref
 
Wina, E. (2010). Utilization of tannin containing shrub legumes for small ruminant production in Indonesia. WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences, 20(1), 21-30.
 
Woodward, S. L., Waghorn, G. C., Watkins, K. A. and Bryant, M. A. (2009). Feeding birdsfoot trefoil reduces the environmental impacts of dairy farming. Proceeding of the New Zealand Society of Animal Production, 69, 179-183.
 
Yang, K., Wei, C., Zhao, G. Y., Xu, Z. W., & Lin, S. X. (2017). Effects of dietary supplementing tannic acid in the ration of beef cattle on rumen fermentation, methane emission, microbial flora and nutrient digestibility. Journal of animal physiology and animal nutrition, 101(2), 302-310.
Crossref