Integrity Research Journals

ISSN: 2536-7099
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASVM
Start Year: 2016

Comparative effect of ethanol extract of Moringa oleifera leaf and Boo-Sta Plus on the body weight and haematological indices of Wister albino rats   |   Article Number: EF00904C8   |   Vol.8 (5) - October 2023

Received Date: 08 June 2023   |   Accepted Date: 04 August 2023  |   Published Date: 30 October 2023

Authors:  Ada Ak. Akwari* , Etah E. Nkanu and Elvis M. Ayim

Keywords: Moringa oleifera, Artificial booster, Boo-Sta Plus, dietary fortification, haematological indices

The comparative effects of ethanol extract of Moringa oleifera and  Boo-Sta Plus on the red blood cell indices and body weight of Wistar albino rats were investigated. Fortification of food is not just trending in the human diet but also in the animal diet. Boo-Sta Plus have been employed in dietary fortification to achieve better results in meat quality, protein mass and weight gain, however, these artificial fortification causes antibiotic resistance and may have other negative health implications. Focus is now being directed on plant-based alternatives such as Moringa oliefera to curb these negative effects. Fresh leaves of Moringa oleifera were washed, oven dried and ground. Twenty (20) Wistar rats weighing (150-170 g) were divided into four groups containing five rats in each group (A, B, C and D). Rats in group A (control) received normal rat chow feed and water. Group B was fed 200 mg/kg body weight Moringa extract (low dose), Group C received 400 mg/kg body weight (high dose) and Group D received Boo Sta-Plus. All the experimental groups received their respective treatment in addition to feeding and water. Weekly body weight was recorded during the duration of 21 days of administration of leaf extract. At the end of 21 days of treatment, blood samples were obtained through cardiac puncture and analysed for haematological indices. The results show that Moringa oleifera leaf extract (low dose) and  Boo-Sta Plus caused a significant increase (p < 0.05) in the RBC, Hb, PCV, whereas a high dose of the leaf extract caused a decrease in the red blood cell indices when compared with the control. The administration of extract caused weight increase at a high dose comparatively to the  Boo-Sta Plus and control. It is therefore concluded that ethanol extract of Moringa oleifera has positive effects on blood parameters and body weight and could serve as a substitute for Boo-Sta Plus thereby curbing the adverse health implications of artificial boosters.

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