JOURNAL OF ANIMAL SCIENCE AND VETERINARY MEDICINE
Integrity Research Journals
ISSN: 2536-7099
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASVM
Start Year: 2016
Email: jasvm@integrityresjournals.org
Comparative effect of ethanol extract of Moringa oleifera leaf and Boo-Sta Plus on the body weight and haematological indices of Wister albino rats
https://doi.org/10.31248/JASVM2023.385 | Article Number: EF00904C8 | Vol.8 (5) - October 2023
Received Date: 08 June 2023 | Accepted Date: 04 August 2023 | Published Date: 30 October 2023
Authors: Ada Ak. Akwari* , Etah E. Nkanu and Elvis M. Ayim
Keywords: Moringa oleifera, Artificial booster, Boo-Sta Plus, dietary fortification, haematological indices
The comparative effects of ethanol extract of Moringa oleifera and Boo-Sta Plus on the red blood cell indices and body weight of Wistar albino rats were investigated. Fortification of food is not just trending in the human diet but also in the animal diet. Boo-Sta Plus have been employed in dietary fortification to achieve better results in meat quality, protein mass and weight gain, however, these artificial fortification causes antibiotic resistance and may have other negative health implications. Focus is now being directed on plant-based alternatives such as Moringa oliefera to curb these negative effects. Fresh leaves of Moringa oleifera were washed, oven dried and ground. Twenty (20) Wistar rats weighing (150-170 g) were divided into four groups containing five rats in each group (A, B, C and D). Rats in group A (control) received normal rat chow feed and water. Group B was fed 200 mg/kg body weight Moringa extract (low dose), Group C received 400 mg/kg body weight (high dose) and Group D received Boo Sta-Plus. All the experimental groups received their respective treatment in addition to feeding and water. Weekly body weight was recorded during the duration of 21 days of administration of leaf extract. At the end of 21 days of treatment, blood samples were obtained through cardiac puncture and analysed for haematological indices. The results show that Moringa oleifera leaf extract (low dose) and Boo-Sta Plus caused a significant increase (p < 0.05) in the RBC, Hb, PCV, whereas a high dose of the leaf extract caused a decrease in the red blood cell indices when compared with the control. The administration of extract caused weight increase at a high dose comparatively to the Boo-Sta Plus and control. It is therefore concluded that ethanol extract of Moringa oleifera has positive effects on blood parameters and body weight and could serve as a substitute for Boo-Sta Plus thereby curbing the adverse health implications of artificial boosters.
| Anwar, F., Latif, S., Ashraf, M., & Gilani, A. H. (2007). Moringa oleifera: a food plant with multiple medicinal uses. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 21(1), 17-25. https://doi.org/10.1002/ptr.2023 |
||||
| Bharali, R., Tabassum, J., & Azad, M. R. H. (2003). Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pacific Journal of Cancer Prevention, 4(2), 131-140. | ||||
| Chattopadhyay, S., Maiti, S., Maji, G., Deb, B., Pan, B., & Ghosh, D. (2011). Protective role of Moringa oleifera (Sajina) seed on arsenic-induced hepatocellular degeneration in female albino rats. Biological Trace Element Research, 142(2), 200-212. https://doi.org/10.1007/s12011-010-8761-7 |
||||
| Chauhan, B., Kumar, G., Kalam, N., & Ansari, S. H. (2013). Current concepts and prospects of herbal nutraceutical: A review. Journal of Advanced Pharmaceutical Technology & Research, 4(1), 4-8. https://doi.org/10.4103/2231-4040.107494 |
||||
| Cheenpracha, S., Park, E. J., Yoshida, W. Y., Barit, C., Wall, M., Pezzuto, J. M., & Chang, L. C. (2010). Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits. Bioorganic & Medicinal Chemistry, 18(17), 6598-6602. https://doi.org/10.1016/j.bmc.2010.03.057 |
||||
| Dacie , J. V., & Lewis, S. M (2002). Practical haematology (10th edition). Edinburgh, churchil Livingstone. | ||||
| Fadi, C., Andrzj, P., Ekaterina, M., & Hayes, K. C. (2010). Nutritional correlates and dynamics of diabetes in the Nile rat (Arvicanthis niloticus): a novel model for diet-induced type 2 diabetes and the metabolic syndrome. Nutrition & Metabolism, 7, Article number 29. https://doi.org/10.1186/1743-7075-7-29 |
||||
| Faye, B., Bucheton, B., Bañuls, A. L., Senghor, M. W., Niang, A. A., Diedhiou, S., Konaté, O., Dione, M. M., Hide, M., Mellul, S., & Gaye, O. (2011). Seroprevalence of Leishmania infantum in a rural area of Senegal: analysis of risk factors involved in transmission to humans. Transactions of the Royal Society of Tropical Medicine and Hygiene, 105(6), 333-340. https://doi.org/10.1016/j.trstmh.2011.02.009 |
||||
| Fuglie, L. J. (2001). The Miracle Tree: Moringa oleifera: Natural Nutrition for the Tropics. Training Manual. Church World Service, Dakar, Senegal. | ||||
| Hekmat, S., Morgan, K., Soltani, M., & Gough, R. (2015). Sensory evaluation of locally-grown fruit purees and inulin fibre on probiotic yogurt in Mwanza, Tanzania and the microbial analysis of probiotic yogurt fortified with Moringa oleifera. Journal of Health, Population, and Nutrition, 33(1), 60-67. | ||||
| Joshi, P., & Mehta, D. (2010). Effect of dehydration on the nutritive value of drumstick leaves. Journal of Metabolomics And Systems Biology, 1(1), 5-9. | ||||
| Mahajan, S. G., & Mehta, A. A. (2010). Immunosupressive activity of ethanolic extract of seed of Moringa oleifera Lam in experimental immune inflammation. Journal of Ethnopharmacology, 130(1),183-186 https://doi.org/10.1016/j.jep.2010.04.024 |
||||
| Marinac, J. S., Colleen, L. B., Lincoln, A. G., James, M. W., Chao, S., & Sandra, K. W. (2007). Supplements: A Survey of Use, Attitudes, and Knowledge Among Older Adults. The Journal of the American Osteopathic Association, 107(1), 13-23. | ||||
| Mbah, B. O., Eme, P. E., Paul, A. E. (2012). Effect of drying techniques on the proximate and other nutrient composition of Moringa oleifera leaves from two areas in eastern Nigeria. Pakistan Journal of Nutrition, 11(11), 1044-1048. https://doi.org/10.3923/pjn.2012.1044.1048 |
||||
| Moon, K., Guallar, E., & Navas-Acien, A. (2012). Arsenic exposure and cardiovascular disease: An updated systematic review. Current Atherosclerosis Reports, 14(6), 542-555. https://doi.org/10.1007/s11883-012-0280-x |
||||
| Moyo, B., Masika, P. J., Hugo, A., & Muchenje, V. (2011). Nutritional characterization of Moringa (Moringa oleifera Lam.) leaves. African Journal of Biotechnology, 10(60), 12925-12933. https://doi.org/10.5897/AJB10.1599 |
||||
| Puvača, N., Stanaćev, V., Glamočić, D., Lević, J., Perić, L., & Milić, D. (2013). Beneficial effects of phytoadditives in broiler nutrition. World's Poultry Science Journal, 69(1), 27-34. https://doi.org/10.1017/S0043933913000032 |
||||
| Rakesh, S., & Singh, V. J. (2011). Antiinflammatory activity of Moringa oleifera leaf and pod extracts against carrageenen induced paw edema in albino mice. Pharmacol Online, 1, 140-144. | ||||
| Saini, R. K., Manoj, P., Shetty, N. P., Srinivasan, K., & Giridhar, P. (2016). Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model. Journal of Food Science and Technology, 53, 511-520. https://doi.org/10.1007/s13197-015-1828-x |
||||
| Saini, R. K., Shetty, N. P., Prakash, M., & Giridhar, P. (2014). Effect of dehydration methods on retention of carotenoids, tocopherols, ascorbic acid and antioxidant activity in Moringa oleifera leaves and preparation of a RTE product. Journal of food science and technology, 51, 2176-2182. https://doi.org/10.1007/s13197-014-1264-3 |
||||
| Shahidi, F. (2012). Nutraceuticals, functional foods and dietary supplements in health and disease. Journal of Food and Drug Analysis, 20(1), 226-230. https://doi.org/10.38212/2224-6614.2144 |
||||
| Zongo, U. Z., Savadogo, A., & Traoré, A. S. (2013). Nutritional and clinical rehabilitation of severely malnourished children with Moringa oleifera. Leaf powder in Ouagadougou (Burkina Faso). Food Nutritional Science, 4, 991-997. https://doi.org/10.4236/fns.2013.49128 |
||||
Copyright © 2025 Integrity Research Journals. All rights reserved.