Integrity Research Journals

ISSN: 2536-7099
Model: Open Access/Peer Reviewed
DOI: 10.31248/JASVM
Start Year: 2016

Sequential effects of experimental Newcastle disease virus on performance and severity of clinical manifestation of the disease in three indigenous Nigerian genotypes of chickens   |   Article Number: 983429234   |   Vol.7 (6) - December 2022

Received Date: 04 November 2022   |   Accepted Date: 05 December 2022  |   Published Date: 30 December 2022

Author:  Yeigba B. Japhet

Keywords: performance., genotypes, Clinical manifestation, indigenous chickens, Newcastle virus

Newcastle disease has been identified as a killer viral infection associated with high case fatality in poultry. This study was conducted to evaluate the sequential effects of experimental Newcastle disease on the performance and severity of clinical manifestation of the disease in three indigenous Nigerian genotypes of chickens. A total of 180 day-old Nigerian indigenous chicks consisting of 60 Naked necks (NN), 60 Frizzle feathers (FF) and 60 Normal feathers (NF) (45 experimental and 15 control per genotype) were used for the study. These chicks had no symptoms of Newcastle disease at the commencement of the experiment. Birds were fed on starter ration (20% CP and 2800 Kcal ME/kg) from day-old to 8th week of age, and growers ration (16% CP and 2750 Kcal ME/kg) from the 9th to 16th week. Fifteen (15) vials of lyophilised Newcastle live virus Kudu 113 strain were obtained from National Veterinary Research Institute, Vom Plateau State, and each vial was diluted with 2 ml of sterile phosphate buffer saline (pH 7.2). Each experimental genotype was inoculated through intra-crop injection with 0.2 ml of the virus in the 5th week. The control group was inoculated 0.2 ml of normal saline. Post infection (PI) observable clinical signs were assessed and live weight changes were determined. Patent Newcastle Disease infection manifested clinical signs included greenish watery diarrhoea, insomnines, ruffled feathers, sneezing and coughing, wherein all of these obvious clinical signs manifested in 90, 31 and 25% of infected NN, NF and FF respectively by day 14 PI. The mortality pattern by day 42 was 94% NF, 100% FF and 79% NN. The study concluded that live-weight changes in the naked neck subsequently increased by day 35 and 42 post infection and the NF had the same sequential result. The study recommended that the NN genotype should be raised in places that are not endemic to Newcastle disease.

Adu, F. D., Edo, U., & Sokoto, B. (1986). Newcastle disease: The immunological status of Nigerian local chickens. Tropical Veterinarian, 4(2), 149-152.
Akinoluwa, P. O., Salako, A. E., Emikpe, B. O., Adeyeo, S. A., & Ogie, A. J. (2012). The differential susceptibility of Yoruba ecotype Nigerian indigenous chicken varieties to Newcastle disease. Nigerian Veterinary Journal, 33(3), 427-429.
Aldous, E. W., & Alexander, D. J. (2008). Newcastle disease in pheasants (Phasianus colchicus): A review. Veterinary Journal, 175,181-185.
Alexander, D. J. (2000). Newcastle disease and other avian paramyxoviruses. Revue Scientifique et Technique-Office International des Epizooties, 19(2), 443-455.
Alexander, D. J. (2001). Newcastle disease. British Poultry Science. 42, 5-22.
Alexander, D. J. (1997) Newcastle disease and other paramyxovirus infections. In: Calnek, B. W., Barnes, H. J., McDougall, L. R., Saif, Y. M., & Beard, G. W. (ed). Diseases of poultry, Iowa State University Press, Ames, Pp. 541-569.
Allan, W. H., & Gough, R. E. (1974). A standard haemagglutination inhibition tests for Newcastle disease (1). A comparison of macro and micro methods. Veterinary Record, 95, 120-123.
Amarasinghe, G. K., Arechiga, C. N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Cai, Y., Calisher, C. H., Campos, L. C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O., Domier, L. L., Durrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarria, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiang, D., Kityo, R., Kobinger, G. P., Kondo H, Koonin EV, Krupovic M, Kurath G, Lamb RA, Lee B, Leroy EM, Maes P, Maisner A., Marston, D. A., Mor, S. K., Muller, T., Muhlberger, E., Ramirez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Paweska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vazquez-Moron, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Ye, G., Zhang, Y. Z., & Kuhn, J. H. (2018). Taxonomy of the order Mononegavirales. Archives of Virology, 163(8), 2283-2294.
Anzaku, S. A., Umoh, J. U., Abdu, P. A., Kabir, J., & Bala, A. (2014). Serological study of Newcastle disease in local chickens in the federal capital territory, Abuja, Nigeria. Scientific Journal of Veterinary Advances, 3(10), 101-103.
Brattt, M, A., & Clavell, L. A. (1972). Haemolytic interaction of Newcastle diseases virus and chicken erythrocytes. 1. Quantitative comparison procedure. Applied Microbiology, 23, 454-460.
Cattoli, G., Susta, L., Terregino, C., & Brown, C. (2011). Newcastle disease: A review of field recognition and current methods of laboratory detection. Journal of Veterinary Diagnostic Investigation, 23(4), 637-656.
El-Safty, S. A., Ali, U. M., & Fathi, M. M. (2006). Immunological parameters and laying performance of naked neck and normally feathered genotypes of chicken under winter conditions of Egypt. International Journal of Poultry Science, 5(8), 780-785.
Fayeye, T. R., Ayorinde, K. L., Ojo, V., & Adesina, O. M. (2006). Frequency and influence of some major genes on body weight and body size parameters of Nigerian local chickens. Livestock Research for Rural Development, 18(3).
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Hassan, M. K., Afify, M. A., Aly, M. M. (2004). Genetic resistance of Egyptian chickens to infectious Bursal disease and Newcastle disease. Tropical Animal Health and Production, 36, 1-9.
Msoffe, P. L. M., Mtambo, M. M. A., Minga, U. M., Gwakisa, P. S., Mdegela, R. H., & Olsen, J. E. (2002). Productivity and natural disease resistance potential of free-ranging local chicken ecotypes in Tanzania. Livestock Research for Rural Development, 14(3).
Ogie, A. J., Salako, E. A., Emikpe, B. O., Amosun, E. A., Adeyemo S. A., & AkinOluwa, P. O. (2012). The possible genetic influence on the susceptibility of exotic, fulani and yoruba ecotype indigenous chickens to experimental Salmonella enteritidis. Livestock Research for Rural Development, 24, Article 193.
OIE (2012). Newcastle disease. manual of diagnostic tests and vaccines for terrestrial animals. Chapter 2.3.14.
Oladele, S. B., Ogundipe, S., Ayo, J. O., & Esievo, K. A. N. (2001). Effects of season and sex on packed cell volume, haemoglobin and total protein of indigenous pigeons in Zaria, Northern Nigeria Veterinarski Arhiv, 71(5), 277-286.
Sa'idu, L., Bisalla, M., & Moumoni, B. (2006). Response of local breeds of chicken to challenge with Newcastle disease virus (Kudu 113 Strain). Journal of Animal and Veterinary Advances, 5(11), 975-979.
SAS (1999). SAS User Guide. Statistical Analysis Institute. Inc. Cary. North Carolina.
Yonash, N, Cheng, H. H., Hillel, J., Heller, D. E., & Cahaner, A. (2001). DNA microsatellites linked to quantitative trait loci affecting antibody response and survivalrate in meat-type chickens. Poultry Science, 80(1), 22-28.