Integrity Research Journals

Model: Open Access/Peer Reviewed
DOI: 10.31248/JDPS
Start Year: 2016

Bryophyllum pinnatum: A mini review on Ethnobotany and Phytochemistry   |   Article Number: 5D75E2F41   |   Vol.2 (1) - April 2018

Received Date: 17 October 2017   |   Accepted Date: 18 December 2017  |   Published Date: 30 April 2018

Authors:  Oladoye S. O. , Ayodele E. T. and Idowu O. T.

Keywords: Bryophyllum, flavonoids, glycosides, phytochemistry.

Bryophyllum pinnatum is from the family crassuliaceae. It is used in folk medicine to treat ailments such as dysentery, hypertersion, boil and so on. It contains a wide range of active phytochemical compounds including alkaloids, terpenes, glycosides and flavonoids. It has been known to process some biological activities This review focus on its biological activities, phytochemistry and its ethnomedicinal uses.

Akinpelu, D. A. (2000). Antimicrobial activity of Bryophyllum Pinnatum leaves. Fitoterapia. 71(2), 193-194.
Anonymous (2006a). Germplasm Resources Information Network (GRIN). National Germplasm Resources Laboratory, National Genetic Resources Program, Agricultural Research Service (ARS), United States Department of Agriculture (USDA), Beltsville, Maryland, USA.
Anonymous (2006b). Mother of millions. Bryophyllum species. Natural Resources and Water Facts - pest series. The State of Queensland (Department of Natural Resources and Water), Brisbane, Queensland. p. 33
Anonymous (2006c). National List of Naturalised Invasive and Potentially Invasive Garden Plants. Version 1.2. World Wildlife Fund - Australia (WWF Australia).
Anonymous (2007a). NSW Department of Primary Industries. NSW Department of Primary Industries, Orange, New South Wales.
Anonymous (2007b). Weeds Australia. National Weeds Strategy Executive Committee, Launceston, Tasmania
Auld, B. A., & Medd, R. W. (1996). Weeds: an illustrated botanical guide to weeds of Australia. Inkata Press, Sydney, New South Wales.
Costa, S., Jossang, A., & Bodo, B. (1995). Propietes biologiques et phytochiie des Kalanchoe pinnata, Systematique ecophysiologie et phytochimie Paris: Karthala. 219-235.
Da Silva, S. A., Costa, S. S, Mendonca, S. C, Silva, E. M., Moraes, V. L., & Bergmann, B. R. (1995). Therapeutic effect of oral Kalanchoe Pinnata leaf extract in murine leishmaniasis. Acta Tropica. 60 (3), 201-210.
De Lange, P. J., Gandner, R. O., Sykes, W. R., Crowcroft, G. M., Cameron, E. K., Stalker, F., Christian, M. L. and Braggins, J. E. (2005). Vascular flora of Norfolk Island: some additions and taxonomic notes. New Zealand Journal of Botany, 43, 563-596.
Del-Rio, B. G., Obdululio, J. C., Marin, F. G., & Ortuno, A. (1997). Uses and properties of citrus flavonoids. J. Agric. Food Chem. 45, 4505-4515.
Donatus, E. O., & Fred, U. N. (2011). Two novel flavonoids from Bryophyllum pinnatum and their antimicrobial Activity. J. Chem. Pharm. Res., 3(2),1-10.
Engler (1926). Die naturrlichen Pflanzenfamilien nebst ihren Gattugen and wichtigen Arten insbesondre der Nutpflanzen. Leipzig: W. Engelmann. Pp. 402-412.
Everett, J., & Norris, E. H. (1990). Crassulaceae. In: Flora of New South Wales, Volume 1 (ed: G. Harden). New South Wales University Press, Kensington, New South Wales.
Gardner, C. D., Lawson, L. D., Block, E., Chatterjee, L. M., Kiazand, A., Balise, R. R., & Kraemer, H. C. (2007). Effect of Raw Garlic vs Commercial Garlic Supplements on Plasma Lipid Concentrations in Adults with Moderate Hypercholesterolemia: A Randomized Clinical Trial. Archives of Internal Medicine 167(4), 346-53.
Gill, L. S. (1992). Ethno-medical uses of plant in Nigeria: UNIBEN Press. p. 46
Green, P. (1994). Flora of Australia, Volume 49, Oceania Islands 1. Australian Biological Resources Study and CSIRO Publishing, Canberra, ACT.
Guaind, K., & Gupta, R. (1972). Alkanes, Alkanols, Triterpenes, and Sterols of Kalanchoe Pinnata. Phytochemistry, 11, 1500-1502.
Hannan-Jones, M. A., & Playford, J. (2002). The Biology of Australian Weeds. 40. Bryophyllum Salisb. species. Plant Protection Quarterly, 17, 42-57.
Haslalka, G. V., Patil, C. R., & Patil, M. R. (2007). Protective effect of Kalanchoe pinnata pers. (Crassulaceae) on gentamicin-induced nephrotoxicity in rats. Indian J. Pharmacol., 39(4), 201-205.
Jain, V., Patel, N., Shah, D., Patel, P., & Joshi, B. (2010). Antioxidant and Antimicrobial Activities of Bryophyllum Calycinum Salisb Leaf, Pharmacology online, 1, 393-405.
Jaiswal, S., & Sawhney, S., (2006). Correlation of epiphyllous bud differentiation with foliar senescence in crassulacean succulent Kalanchoe pinnata as revealed by thidiazuron and ethrel application. J. of Plant Physiology. 163, 717-722.
Kamboj, A., Saluja, A. K. (2005). Bryophyllum pinnatum (Lam.) Kurz.: Phytochemical and pharmacological profile: A review. Pharmacognosy Review, 3(6), 364-374.
Kirtikar, K. R., & Basu, B. D. (2001): Indian medicinal plants, vols.1-4. Dehradun, India; Oriental Enterprise.
Liu, K. C. S., Yang, S. L., & Roberts, M. F. (1989). Phillipson J D. Eupafolin rhamnosides from Kalanchoe gracilis. Journal of Natural Products, 52, 970–974.
Marriage, P. B., & Wilson, D. G. (1971). Analysis of the organic acids of Bryophyllum calycinum. Canadian journal of biochemistry, 49(3), 282-296.
McKenzie, R. A., Franke, F. P., & Dunster, P. J., (1987). The toxicity to Cattle and Bufadienolide content of six Bryophyllum species. Aust Vet J., 64(10), 298-301.
Muzitano, M. F., Luzineide, W. T., Catherine, G., Kaiser, C. R., RossBergmann, B., & Costa, S. S. (2006). The antileishmanial activity assessment of unusual flavonoids from Kalanchoepinnata. Phytochemistry, 67, 2071- 2077.
Nielsen, A. H., Olsen, C. E., & Moller, B. L., (2005). Flavonoids in flowers of 16 Kalanchoe blossfeldiana varieties. Phytochemistry, 66(24), 2829-35.
Obaseiki-Ebor, E. E. (1985). Preliminary report on the in-vitro antibacterial activity of Bryophyllum pinnatum leaf juice. Afr J Med Med Sci. 14(34), 199-202.
Pal-Bhadra, M., Bhadra, U., & Birchler, J. A. (1999). Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences. Cell, 99(1), 35-46.
Pal, S., & Chaudhuri, A. N. (1991). Studies on the anti-ulcer activity of a Bryophyllum pinnatum leaf extract in experimental animals. Journal of Ethnopharmacology, 33(1-2), 97-102.
Ojewole, J. A. O. (2005). Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract. Journal of Ethno pharmacology, 99, 13-19.
Okwu, D. E., & Josiah, C. (2006). Evaluation of the chemical composition of two Nigerian medicinal plants. African Journal of Biotechnology; 5(4), 357-361.
Okwu, D. E., & Okwu, M. E. (2004). Chemical Composition of Spondias mombin Linn plant parts. J. Sustain Agric. Environ. 6(2), 140-147.
Orisakeye, O. T., Oladoye, S. O., & Peters, O. A. (2015). Chemical Composition and Antioxidant Activity of Bryophyllum pinnatum Root. Natural Products Chemistry and Research, 3(3), 1-3.
Pal, S., & Nag Chaudhari, A. K. (1992). Further studies on anti-inflammatory profile of the methanolic fraction of the fresh leaf extract of Bryophyllum pinnatum. Fitoterapia. 63, 451-459.
Paranjpe, P., (2005). Indian Medicinal Plants had forgotten Healers. Chaukhamba Sanskrit Pratisthan, Delhi. 194-195.
Quazi Majaz, A., Tatiya, A. U., Khurshid, M., Nazim, S., & Siraj, S. (2011). The miracle plant (Kalanchoe pinnata): a phytochemical and pharmacological review. International Journal of Research in Ayurveda and Pharmacy, 2(5), 1478-1482.
Radford, D. J., Gillies, A. D., & Hinds, J. A. (1986). Naturally occurring cardiac glycoside. Med. J. Aust. 144, 540-544.
Randall, R. P. (2012). A Global toCompendium of Weeds. Second Edition. Department of Agriculture and Food, Western Australia. 1125.
Rastogi, R. P., & Mehrotra, B. N. (1991). Compend. Indian Med. Plants. PID. New Dehli. 2, 112.
Salah, N., Miller, N. J., Pagange, G., Tijburg, L., Bolwell, G. P., Rice, E., & Evans, C. (1995). Polyphenolic flavonoids as scavenger of aqueous phase radicals as chain breaking antioxidant. Arch Biochem. Broph, 2, 339-346.
Sofowora, A. (1993). Medicinal plants and traditional medicine in Africa. New York: John Wiley and Sons. p. 119.
Tatsimo, S. J. N, Tamokou, J. D, Havyarimana, L., Csupor D., Forgo P., Hohmann J., Kuiate J. R., & Tane, P. (2012). Antimicrobial and antioxidant activity of kaempferol rhamnoside derivatives from Bryophyllum pinnatum. BMC Research Notes, 5,158.
Umebese, C. E., & Falana, F. D. (2013). Growth, phytochemicals and antifungal activity of Bryophyllum pinnatum L. subjected to water deficit stress. African Journal of Biotechnology, 12(47), 6599-6604.
Yadav, N. P., & Dixit, V. K. (2003). Hepatoprotective activity of leaves of Kalanchoe Pinnata Pers. Journal of Ethnopharmacology. 86, 197-202.
Yemitan O. K., & Salahdeen, H. M. (2005). Neurosedative and muscle relaxant activities of aqueous extract of Bryophyllum pinnatum. Fitoterapia. 76:187-193.